Allegro 3D Receives Almost $1M in Grant Award to Develop Bioprinter

  • Allegro 3D Receives Almost $1M in Grant Award to Develop Bioprinter

    updated 2 weeks, 4 days ago 1 Member · 1 Post
  • Anonymous

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    April 29, 2021 at 10:20 AM
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    Bioprinting company Allegro 3D has been awarded a National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase II grant for $997,692. The grant money will support the development of a next-generation high-throughput 3D bioprinter for fabricating tissue models at the industrial scale to advance drug discovery and assay development. 

    Led by principal investigator and Allegro 3D’s CEO Wei Zhu, the project was previously awarded an SBIR Phase I funding of $299,281 in 2019. The grant was destined for research and development work on a high throughput optical projection (hTOP) bioprinter that could directly print human liver tissue models for applications in preclinical drug screening. During the Phase I grant duration, Allegro 3D focused on developing the hTOP bioprinter and learning how to use it to create 3D hydrogel constructs within a well cell culture plate.

    Ultimately, the Phase I stage research aimed to demonstrate the use of hTOP to bioprint in vitro functional human liver tissues using human induced pluripotent stem cells (iPSC). These models are expected to facilitate preclinical drug screening and disease studies, leading to a significant reduction in drug development costs and time to clinical use, significantly improving the public health system. Attempting to optimize and

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